Role of interleukin-8 in uveitis pathogenesis
10.3760/cma.j.issn.2095-0160.2014.07.016
- VernacularTitle:白细胞介素-8在葡萄膜炎发病机制中的作用
- Author:
Zhenhua, WANG
- Publication Type:Journal Article
- Keywords:
Uveitis;
Interleukin-8;
Cytokine;
Chemokine
- From:
Chinese Journal of Experimental Ophthalmology
2014;32(7):648-652
- CountryChina
- Language:Chinese
-
Abstract:
The etiology of uveitis is very complicated and the pathogenesis is not yet clear.In recent years,more and more evidences imply that the chemokines interleukin-8 (IL-8) is involved in the development of uveitis.Studies of IL-8 and its network features contribute to the understanding of uveitis pathogenesis and provide an important foundation for seeking new indication of activity of uveitis and new treatment target.This paper summarizes the progression in the study on IL-8 in uveitis,including the physiology functions of IL-8,mechanisms for ocular inflammatory,and the role and performance of IL-8 in uveitis.
