MicroRNAs and intraocular cancer
10.3760/cma.j.issn.2095-0160.2014.04.021
- VernacularTitle:微小RNAs与眼内恶性肿瘤
- Author:
Yuan, ZHANG
- Publication Type:Journal Article
- Keywords:
MicroRNA;
Intraocular cancer;
Retinoblastoma;
Chroidal malignant melanoma
- From:Chinese Journal of Experimental Ophthalmology
2014;32(4):376-379
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs are approximately 22 nt non-coding RNAs,which belong to a class of regulatory RNAs.MicroRNAs are determined to be involved in the expression of gene and oncogenesis with remarkable tissue specificity.The study of the microRNAs opens a new era for the understanding of small non-coding RNAs.Intraocular cancer is a complex of genetic diseases caused by abnormalities of gene structure and expression,moreover,expression of microRNAs is associated with intraocular cancer and they could have a crucial function in tumor progression.Here the emerging knowledge of microRNAs contributing to intraocular cancer was briefly reviewed.
