Recent advances in diabetic cataract advanced glycation end products and its inhibitors
10.3760/cma.j.issn.2095-0160.2011.08.022
- VernacularTitle:糖尿病性白内障糖基化终末产物及其抑制剂的研究进展
- Author:
Zhao-dong, CHU
;
Yong, YAO
- Publication Type:Journal Article
- Keywords:
Advanced glycation end products;
Glycosylation;
Diabetic cataract
- From:
Chinese Journal of Experimental Ophthalmology
2011;29(8):760-763
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic cataract is an metabolic-type cataract. Its pathogenesis mechanism is not completely clear. Researches demonstrated that glycosylation plays an increasingly important role in the formation of diabetic cataract,and increased blood glucose level promote the pathogenesis and progression of diabetic disease by accelerate the glycosylation response. Therefore, more researches on advanced glycation end products(AGEs) and its inhibitors is being concerned. The advance in the study of AGEs concept, its effect on diabetic cataract formation, the influence of AGEs inhibitor on diabetic cataract are summarized in this article.
