Thyroglobulin and thyroglobulin antibody in differential diagnosis between differentiated thyroid carcinoma and nodular goiter
10.3760/cma.j.issn.1674-6090.2013.01.020
- VernacularTitle:甲状腺球蛋白及抗体在结节性甲状腺肿和甲状腺癌的鉴别诊断价值
- Author:
Jinhua LI
;
Fuyang GAO
;
Chengyi LIU
;
Wei DU
;
Jianhui JIANG
;
Shuang ZHAO
- Publication Type:Journal Article
- Keywords:
Nodular goiter;
Differentiated thyroid carcinoma;
Thyroglobulin;
Thyroglobulin antibody
- From:Journal of Endocrine Surgery
2013;7(1):54-55,68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of thyroglobulin(TG) and thyroglobulin antibody (TGAb) in differential diagnosis between nodular goiter and differentiated thyroid carcinoma(DTC).Methods From Jan.2006 to Jan.2007,180 cases of thyroid carcinoma were included in group A(male:45,average age:47 ; female:135,average age:43)and 150 cases of nodular goiter were included in group B (Male:55,average age 43 ; female:95,average age:41).All the cases came from the General Department of Chengde Central Hospital.Group C (the control group) included 120 cases (male:40,average age:38 ; female:80,average age:44).All patients underwent thyroids ultrasound,thyroid function detection and CT.Results The positive rate of TG and TGAb was 40.0％ and 43.3％ in group A,which were obviously higher than those in group B (7.33％,9.33％)and group C(4.17％,7.50％).The difference had statistical significance(P ＜0.05).However,there was no statistical difference between group B and group C (P ＞ 0.05).Conclusion The measurement of TG and TGAb has clinical significance in differential diagnosis between DTC and nodular goiter.
