Influence of alimentary tract reconstruction on gastric cancer patients complicated with type 2 diabetes mellitus (a report of 67 cases )
10.3760/cma.j.issn.1674-6090.2009.01.012
- VernacularTitle:胃转流术对合并2型糖尿病胃癌患者血糖的影响:附67例临床报告
- Author:
Mingang YING
;
Feng HUANG
;
Dong ZHOU
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Stomach neoplasms;
Alimentary tract reconstruction
- From:Journal of Endocrine Surgery
2009;3(1):32-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of alimentary tract reconstruction on blood glucose level in gastric cancer patients complicated with type 2 diabetes mellitus. Methods Clinical data of 67 gastric cancer patients complicated with type 2 diabetes mellitus and the level of blood glucose before operation, one month, three month, six month after operation were retrospectively analyzed. BMI of 53 patients was lower than 25kg/m2,9 patients between 25～29.9 kg/m2 and 5 patients was higher than 30kg/m2 .Total gastrectomy with P-type jejunal pouch Roux-en-Y esophagojejunostomy was performed in 26 cases, and total gastrectomy with Roux-en-Y esophagojejunostomy was performed in 11 cases, distal subtotal gastrectomy with Roux-en-Y gastrojejunostomy in 30 cases. Results Operations on sixty-seven patients were all uneventfully. The mean fasting blood glucose level in the morning was 9.6±3.3 mmol/L before operation, 7.4±2.6 mmol/L one month after operation, 7.5±2.3 mmol/L three month after operation, and 7.7±2.9 mmol/L six month after operation. There were significant differences between the blood glucose level of before operation and one month after operation (P<0.05), and there were no significant differences between three month,six month and one month after operation (P>0.05). Conclusions Alimentary tract reconstruction has obviousinfluence on blood glucose level in type 2 diabetes mellitus patients. It takes about one month for reveal the effect of operation. This phenomenon is of value for clinical application. Its mechanism needs further research.
