Comparision of non-fasting with fasting blood lipid testing in in-hospital patients
10.3760/cma.j.issn.1009-9158.2017.06.006
- VernacularTitle:住院患者空腹与早餐后血脂检测水平的比较
- Author:
Ying GAO
;
Yuanlin GUO
;
Naqiong WU
;
Chenggang ZHU
;
Ping QING
;
Geng LIU
;
Qian DONG
;
Jianjun LI
- Keywords:
Cardiovascular disease;
Triglycerides;
Blood chemical analysis
- From:
Chinese Journal of Laboratory Medicine
2017;40(6):431-435
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility of the application of non fasting blood lipid in the hospitalized population.Methods Self-control study was used.608 patients(aged 20~86 years old) were enrolled from April 2015 to October 2016 in lipid center of FuWai hospital.Fasting sample and non-fasting sample(1~4 h after breakfast) were collected from every patient and lipid profile including TG (triglyceride), TC (total cholesterol), HDL-C (high density lipoprotein cholesterol) and LDL-C (low density lipoprotein cholesterol) were measured in clinical laboratory.The results of two tests were compared using the Wilcoxon signed-rank test.Results The differences between non-fasting and fasting lipid test were +0.47 mmol/l (+30%) for TG,-0.03 mmol/l (-2.8%) for HDL-C,-0.09 mmol/l (-3%) for LDL-C and-0.24 mmol/l (-8.7%) for calculated LDL-C (P<0.001 respectively).The differenceswere +0.01 mmol/l for TC and +0.02 mmol/l for non-HDL-C,therefore no statistical difference was observed.When the TG level was stratified,the level of non-fasting LDL-C using directing test method was not significantly different between TG> 4.5 mmol/L and the whole (0.07 vs.0.09),but the level of non-fasting LDL-C using formula method wassignificantly different between TG> 4.5 mmol/L and the whole (0.66 Vs.0.24),andthe drops were 34.9% vs.8.7%.Conclusion Non-fasting lipid test could be an effective routine method for lipid evaluation in the hospitalized population.
