Progress of relationship between diabetes and papillary thyroid cancer
10.3969/j.issn.1006-6187.2017.07.021
- VernacularTitle:糖尿病与甲状腺乳头状癌的关系
- Author:
Jing NI
;
Ling YUE
- Keywords:
Papillary thyroid cancer;
Diabetes mellitus;
Insulin resistance;
Oxidative stress
- From:Chinese Journal of Diabetes
2017;25(7):670-672
- CountryChina
- Language:Chinese
-
Abstract:
Papillary thyroid cancer (PTC) is the most common type in thyroid carcinomas.Recently,the prevalence and diagnostic rate of PTC has got significantly high with the general use of ultrasound.Nowadays,more and more studies have suggested that the coexistence of PTC and diabetes is common.They indicated that hyperglycemia would induce the deterioration of oxidative stress injury,chronic inflammation,insulin resistance,obesity,dyslipidemia,deficiency of vitamin D and dysimmunity.All of these may break the balance of oxidation and antioxidation and result in disordering signal pathway,accumulation of inflammatory cytokines,over activating of insulin and insulin-like growth factor-1,changing the metabolic pathways,which will promote the occurrence and progression of PTC.
