Factors affecting establishment of rodent alcohol drinking models and recent advances
10.3867/j.issn.1000-3002.2017.06.016
- VernacularTitle:建立啮齿类酒精饮用动物模型的影响因素及研究进展
- Author:
Xin LIU
;
Qianqian ZHANG
;
Shengxia WANG
;
Wangxin ZHANG
;
Hanting ZHANG
- Keywords:
alcohol;
animal strains;
alcohol drinking models;
rodent
- From:
Chinese Journal of Pharmacology and Toxicology
2017;31(6):607-614
- CountryChina
- Language:Chinese
-
Abstract:
Alcohol use disorder (AUD) is one of the main factors that threaten human health and life.WHO data show that about 3.3 million people die each year worldwide due to AUD.AUD has become a global public health concern,but its neurobiological and behavioral mechanisms remain unclear.Therefore,it is particularly urgent to develop valid and reliable animal models to investigate the underlying mechanisms of AUD.This review summarizes the animal species and modeling methods of AUD in order to explore the potential influence on the deviation of modeling in alcohol intake and provide helpful inputs to behavioral research of AUD.
