Role of Dishevelled in Neurogenesis (review)
10.3969/j.issn.1006-9771.2017.05.012
- VernacularTitle:散乱蛋白对神经发生影响的研究进展
- Author:
Zhimin WANG
;
Caiqin MEI
- Keywords:
Dishevelled;
Wnt signaling;
neurogenesis;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2017;23(5):548-552
- CountryChina
- Language:Chinese
-
Abstract:
Dishevelled (Dvl) is a kind of protein widely existing in human tissue, containing three structural domains:Dishevelled and Axin (DIX);postsynaptic density protein-95, disc large tumour suppressor, zonula occludens-1 (PDZ);and Dishevelled, Egl-10 and pleck-strin (DEP). Dvl participates in the Wnt signaling through different structure domains to play a role in nervous system development and neu-rogenesis after nerve injury.