Advances of Molecular Mechanisms on Obesity Inducing Muscle Atrophy (review)
10.3969/j.issn.1006-9771.2017.05.013
- VernacularTitle:肥胖性肌肉萎缩的分子机制研究进展
- Author:
Lin LUO
;
Jinpeng YANG
;
Songtao WANG
;
Xin LIAO
;
Wei ZHAN
- Keywords:
obesity;
muscle atrophy;
signal pathway;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2017;23(5):553-557
- CountryChina
- Language:Chinese
-
Abstract:
Obesity is becoming a chronic epidemic worldwide. Persistent obesity, in addition to triggering changes in skeletal muscle function and structure, may also lead to the occurrence of skeletal muscle atrophy, that maybe associate with autophagy and ubiquitin protea-some, interleukin-6, leptin, adiponectin, interleukin-10, tumor necrosis factor-alpha, growth hormone, angiotensin II, glucocorticoid, ad-vanced glycation end-product and myostatin, etc.
