Clinical values of serum neuron-specific enolase in lung cancer
- VernacularTitle:血清NSE表达水平对肺癌的诊断及治疗价值
- Author:
Rui LIU
;
Li LI
- Publication Type:Journal Article
- Keywords:
lung neoplasms/diagnosis;
tumor marker,biological;
neuron-specific enolase;
phosphopyruvate hydratase/blood
- From:
Journal of Jilin University(Medicine Edition)
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical values of neuron-specific enolase(NSE) as serum tumor marker in lung cancer.Methods The serum NSE levels in 96 patients with lung cancer,60 patients with begnign pulmonary disease and 60 healthy controls were measured by using enzyme-linked immunosorbent assay.Results The levels of NSE in serum in patients with lung cancer was significantly higher than those in healthy subjects and patients with begnign lung disease(P0.05).The effective rate of chemotherapy were 87.10%,40.00% and 66.67%, 33.33% in patients with SCLC and NSCLC,respective for NSE positive and negative ones(P