Animal model of glycation induced by D-galactose
- VernacularTitle:D-半乳糖致蛋白质糖基化动物模型的建立
- Author:
Shiping ZHANG
- Publication Type:Journal Article
- Keywords:
D-galactose;
aminoguanidine;
glycation
- From:
Basic & Clinical Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a new rat model of glycation.Methods D-galactose((150 mg/kg)) was established in rats by intraperitoneal injection for eight weeks.Methods After continuous administration of D-galactose for eight weeks,the level of two-hour blood glucose、activity of aldose reductase、level of fructosamine in serum、the amount of glycohaemoglobin and advanced glycation end-products are all higher than that of control(P
