Expression of CD40/CD40L in lung tissue of rabbits with hemorrhagic shock
- VernacularTitle:CD40/CD40L在兔失血性休克肺组织中的表达
- Author:
Bin WU
- Publication Type:Journal Article
- Keywords:
Hemorrhagic shock;
CD40;
CD40L;
Lung
- From:Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression and the effects of CD40/CD40L in lung tissue of rabbits with hemorrhagic shock.Methods:18 healthy rabbits were randomly divided into control group(group A),hemorrhagic shock 1 hour group(group B) and hemorrhagic shock 2 hours group(group C),with 6 rabbits in each group.Except the rabbits in the control group,rest rabbits were made into hemorrhagic shock models with lung injury according to Wiggers modified method.TNF-?、IL-10 in plasma were measured by ELISA.Expressions of CD40 and CD40L in lung tissue were measured by immunohistohemistry.Water quantity and pathological change in the lung were observed.Results:The lung of group B and C displayed obvious injury,water quantity increased(P
