Anti-aging Effect of Polysaccharides from Crude and Processed Cornus Officinalis on Mice with Deficiency of Kidney
- VernacularTitle:山茱萸炮制前后多糖成分对肾阴虚模型小鼠的抗衰老作用
- Author:
Ziqin FU
;
Baochang CAI
;
Zongliang YU
;
Yanpeng DAI
- Publication Type:Journal Article
- Keywords:
Polysaccharides from Cornus Officinalis;
Deficiency of kidney;
Anti-aging;
Mice
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the anti-aging effect of polysaccharides from crude and processed Cornus Officinalis on the mice with deficiency of kidney.Methods The mice were given the drugs by gastric perfusion. The effect of polysaccharides on the time of weight-loading swimming, anti-hypoxia time , and serum SOD activity and MDA content in mice with kidney deficiency was observed. Results Compared to the crude Cornus Officinalis, the polysaccharides from the processed product can markedly prolong the time of weight-loading swimming, anti-hypoxia time, promote the activity of SOD and decrease the content of MDA. Conclusions Polysaccharides from Cornus Officinalis have certain anti-aging effect on the mice with deficiency of kidney, and the effect of the processed is superior to that of the crude.