Effect of ethanol precipitation on chlorogenic acid from Flos Lonicerae Japonica
- VernacularTitle:醇沉对纯化金银花中绿原酸工艺的影响
- Author:
Haiyan YANG
;
Fuming CHEN
;
Wu YAN
- Publication Type:Journal Article
- Keywords:
chlorogenic acid;
Flos Lonicerae Japonica ethanol precipitation;
purification
- From:
Chinese Traditional Patent Medicine
1992;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To test the effect of ethanol precipitation on the purifying technology of chlorogenic acid (CGA). METHODS: Using HPLC, the effect of the extraction of CGA from the crude Flos Lonicerae Japonica powder with three concentrations of ethanol was compared. RESULTS: Ethanol with concentration of 60% was optimal. CGA content was raised from 5.5% to 37.72% by use of ethanol precipitation and extraction in combination. CONCLUSION: The ethanol precipitation can get rid of the impurity in the crude powder of Flos Lonicerae Japonica effectively and the yield of CGA can reach 90.16%.
