Anti-aging effects of polysaccharides from rhizomorph of Armillaria mellea
- VernacularTitle:蜜环菌菌索多糖抗衰老作用研究
- Author:
Lei YU
;
Yeshou SHEN
;
Jianmin WU
;
Qunying XIE
- Publication Type:Journal Article
- Keywords:
Armillaria mellea;
rhizomorph polysaccharides;
D-galactose;
anti-aging;
fruit fly;
mouse
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the anti-aging effects of polysaccharides from rhizomorph of Armillaria mellea(ARP) on fruit fly and mouse. METHODS: Regarding fruit files and D-galactose induced aging mice as research objects,observing the fruit flies lifespan;The ability to learn and memorize on model mice were observed by jumping platform test and maze test,the body weight,thymus and spleen index,SOD and GSH-Px activities、MDA and NO levels in serum,liver and brain were measured. RESULTS: ARP could significantly lengthen the lifespan of fruit flies;Obviously improve the ability to learn and memorize,markedly increase the body weight and resist the atrophy of thymus and spleen of model mice,SOD and GSH-Px activities increased obviously,MDA and NO levels decreased dramatically on model mice. CONCLUSION: ARP has anti-aging effects by immune-regulatory and eliminating free radicals.
