Anti-oxidative effect of Jiangtang compound recipe on subacute aging model mice
- VernacularTitle:降糖复方对亚急性衰老模型小鼠的抗氧化作用
- Author:
Juan ZHANG
;
Guanzhong WU
- Publication Type:Journal Article
- Keywords:
Jiangtang compound recipe;
D-galactose;
malondialdehyde;
superoxide dismutarse;
glutathione peroxidase
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To study the effect of antioxidation in subacute aging model mice with Jiangtang compound recipe which composed of kudzuvine root, heartleaf houttuynia herb and Evonymus alatas. METHODS: By using the D-galactose-induced aging mice, the body weight,the content of malondialdehyde (MDA),the activities of superoxide dismutarse(SOD) and glutothine peroxidase(GSH-Px) in serum and tissues were determined. RESULTS:To the model mice, Jiangtang compound recipe (14, 7 g/kg, i.g.) reduced the content of MDA, enhanced the activities of SOD and GSH-Px in serum and tissuses, inhibited the decrease of body weight. CONCLUSION: Jiangtang compound recipe shows a remarkable anti-oxidative effect on the D-galactose-induced aging mice.
