Antitumor activity of different organic solvents extracts and plumbagin from plumbago zeylanica L. on EMT-6 breast cancer and transplanting S180 in vivo
- VernacularTitle:白花丹不同有机溶剂提取物和白花丹醌对移植性乳腺癌和S180肉瘤的作用
- Author:
Jizhong ZHANG
;
Yuan LIU
;
Tao JIAO
- Publication Type:Journal Article
- Keywords:
Plumbago zeylanica L.;
breast cancer;
S180 sarcoma;
laboratory experiment
- From:
Chinese Pharmacological Bulletin
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To find out the effect of the different organic solvents extracts and plumbagin from Plumbago zeylanica L.on EMT-6 breast cancer of BALB/C mouse and transplanted S180 of KM mouse primarily.Method Experiments of animal transplanted tumor in vivo were adopted.Results ① The high dose of chloroform group and plumbagin group could inhibit the growth of EMT-6 breast cancer in BALB/C mice in vivo.Compared with that of physiological saline group,tumor weight has obviously lightened(P
