Efficacy and safety of gabapentin in the treatment of migraine:a double-blind randomized placebo-controlled study
- VernacularTitle:加巴喷丁治疗偏头痛的有效性和安全性——随机、双盲对照研究
- Author:
Lintong GE
;
Li LIN
;
Huijuan WU
;
Jing ZHANG
- Publication Type:Journal Article
- Keywords:
gabapentin;
migraine;
randomized;
double-blind
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To evaluate the efficacy and safety of gabapentin in the treatment of migraine.METHODS:A randomized,double-blind,placebo-controlled study was taken.104 patients(aged 18 to 60 year)with migraine were randomly assigned to receive placebo(control group,49 patients)or gabapentin(experimental group,55 patients)for 4 weeks.The efficacy,side effects,TCD and EEG were assessed at the beginning of trials,and 4th,8th weeks.RESULTS:Comparing with the placebo group,the frequency,duration and intensity of migraine were markedly decreased in gabapentin group,there was significant difference between groups(P0.05).CONCLUSION:Gabapentin is an effective and safe agent from migraine.
