Study on antioxidant activity of Clematis chinensis Osbeck polysaccharide
- VernacularTitle:威灵仙多糖的抗氧化活性研究
- Author:
Yan CHEN
;
Yujun SUN
;
Wei FANG
- Publication Type:Journal Article
- Keywords:
Clematis chinensis Osbeck;
Polysaccharide;
Anti oxidation;
Carbon tetrachloride;
Experimental study
- From:China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the antioxidant activity of Clematis chinensis Osbeck polysaccharide(CCP).Methods:① To assay the scavenging activity of CCP on hydroxyl radical and superoxide anion in vitro.② To analyze the effect of CCP on red blood cell autoxidation hemolysis induced by H2O2 by colorimetry.③ To study the effect of CCP on acute hepatic injury of the mice induced by carbon tetrachloride.Results: CCP could eliminate the hydroxyl free radical and the superoxide anion free radical,reduce red blood cell autoxidation hemolysis induced by H2O2,raise the activities of SOD and GSH-Px in hepatic injury mice's serum and liver apparently,reduce the content of MDA and liver index notably.Conclusion: CCP has the significantly action of anti oxidation activity in vitro and in vivo which relates to removing oxygen free radical.
