Effect of Fiveleaf Gynostemma Herb on hyperlipoidemia and hemorheological changes in rabbits
- VernacularTitle:绞股蓝对兔高脂血症与血液流变学影响的研究
- Author:
Huabing TAN
- Publication Type:Journal Article
- Keywords:
hyperlipoidemia;
hemorheology;
Fiveleaf Gynostemma Herb;
interference
- From:Journal of Third Military Medical University
2003;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study effect of Fiveleaf Gynostemma Herb on hyperlipoidemia and hemorheological changes in rabbits.Methods Forty rabbits were randomly divided as groups A(fed with high fat food plus 5 g/kg Fiveleaf Gynostemma Herb),B(high fat food plus 5 mg/kg simvastatin),C(high fat food),E(standard feedstuff).TG,TC,LDL-C,HDL-C,endothelin-1(ET-1)and hemorheological indexes(blood viscosity,plasma viscosity,erythrocyte aggregation)were checked before experiment and at 9th week after experiment.Ultramicrostructure of endothelial cells was observed.Results TG,TC and LDL-C of groups A,B and C increased gradually.TG,TC,LDL-C of groups A and B were lower than those of group C(P