Relationship between the plasma resistin,obesity and insulin resistance in nonalcoholic fatty liver disease patients.
- VernacularTitle:非酒精性脂肪肝血浆抵抗素与肥胖和胰岛素抵抗关系的研究
- Author:
Rong LIU
;
Xiang YAN
;
Jinchun HE
- Publication Type:Journal Article
- Keywords:
Resistin;
Nonalcoholic fatty liver disease;
Insulin resistance;
Obesity
- From:
Chinese Journal of Practical Internal Medicine
2006;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The study aimed to assess the relationship between the plasma resistin,obesity and insulin resistance and nonalcoholic fatty liver disease(NAFLD).Methods We measured fasting plasma resistin in 60 NAFLD patients and 28 matched normal control subjects from Oct.2005 to Feb.2006.The level of plasma resistin was measured by ELISA method.Insulin resistance by homeostasis model(HOMA),height,weight,waist circumstance,hip girth,waist to hip ratio(WHR),body mass index(BMI),blood pressure,blood glucose,total cholesterol,triglyceride,HDL-cholesterol,LDL-cholesterol,aspartate aminotransferase(AST),alanine aminotransferase(ALT)and fasting insulin were measured as well.Results Plasma resistin levels were higher in NAFLD patients as compared to controls(8.56?2.5 vs 6.39?2.81,P