EFFECTS OF SOYBEAN ISOFLAVONES ON CELL CYCLES,CELL APOPTOSIS AND PROLIFERATION ON THYMOCYTES IN IRRADIATED MICE
- VernacularTitle:大豆异黄酮对电离辐射小鼠胸腺细胞周期、凋亡与增殖的影响
- Author:
Li LIU
;
Hong JIN
;
Zhiqin XU
;
Wenkao NAN
;
Peibing LI
;
Lanxing GAO
- Publication Type:Journal Article
- Keywords:
soybean isoflavones;
radiation;
thymus;
immunology
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the effect of soybean isoflavones(SI) on thymocytes in irradiated mice. Method: Ninety male mice were randomly divided into control group, irradiated group, irradiated plus 0.5% dose SI group. After 2w feeding, the mice received 4.0 Gy 137Cs ?-radiation. The cell cycles,cell apoptosis and proliferation of thymocytes and thymus index were observed in irradiated mice after 12h, 24h, 1w and 2w. Results: After the mice were irradiated, the thymus became significantly atrophic, and the rate of cell apoptos and the cell cycles of G0-G1 phase in thymocytes were significantly increased (P
