Effect of Danhong Zhiganching capsules in rats with experimental fatty liver
- VernacularTitle:丹红脂肝清胶囊对实验性大鼠脂肪肝的作用
- Author:
Yuan LIU
;
Zhen CHEN
;
Zhiyu QIAN
- Publication Type:Journal Article
- Keywords:
non-alcoholic fatty liver;
high fat diet;
Danhong Zhiganching capsule
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To study the effect of Danhong Zhiganching capsules on the experimental fatty liver in rats.METHODS: Male SD rats were treated by high fat diet for 6-week after being treated by a low dose of CCl_4 to induce fatty liver model.Then,drugs were given by oral to the rats,the contents of triglyeride,total cholesterol in serum and liver tissue,the contents of superoxide dismutase and malondialdehyde in serum and the contents of free fatty acids in liver tissue acted as indexes to determine the effect of Danhong Zhiganching capsules.RESULTS: The contents of triglyeride and total cholesterol in serum and liver tissue of rats were significantly reduced by Danhong Zhiganching capsules,and so it is with the contents of free fatty acids in liver tissue(P
