Best formulation and clinical effects of marzulene-S grranuls membrane for oral ulcer
- VernacularTitle:麦滋林-S口腔溃疡膜的处方优选及临床疗效
- Author:
Hong CHEN
;
Lixia ZHOU
;
No WENZHOU
- Publication Type:Journal Article
- Keywords:
marzulene-S;
oral membrane;
orthogonal method;
clinical effect
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To choose the best formulation of marzulene-S grranuls oral membrane and to evaluate the clinical effects.METHODS: Orthogonal method was used for studying.Take the appearance,viscidity and dissolubility of the oral membrane as the indexes of scoring 108 cases of patients were chosen and divided into two groups randomly.58 case were treated with marzulene-S grranuls oral membrane and 50 cases were treated with gargarisma chlorhexidine as the control group.RESULTS: The best prescription is sodium carboxymethyl cellulose 4%,polyvinyl alcohol_(1750) 1% and polyvinyl alcohol_(17-88) 3%.CONCLUSION: The design of the formulation is reasonable and the clinical effect was satisfactory.
