Effects of Rosa roxburghii Tratt extract-CL1 on gastric carcinoma SGC-7901 cells growth and human umbilical cord CD34~+ cells proliferation and differentiation
- VernacularTitle:刺梨提取物CL1对胃癌SGC-7901细胞增殖和人脐血CD34~+造血干/祖细胞增殖分化能力的影响
- Author:
Honglin LIU
- Publication Type:Journal Article
- Keywords:
Rosa roxburghii Tratt;
CL1;
gastric carcinoma;
heamatopoietic stem/progenitor cell;
proliferation;
differentiation
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
(0.05)) CONCLUSION: CL1 has inhibitory effect on growth of SGC-7901 cells in vitro,but does not affect proliferation of CD34~+ and differentiation of CD34~+ haematopoietic stem/progenitor cells to granulocyte and monocytes.This demonstrates that CL1 has anticancer effect,but does not affect the proliferation and differentiation of haematopoietic stem/progenitor cell to granulocytes and monocytes.It may not cause obvious haematopoietic depression.
