Mitochondrial Uncoupling Protein and Cerebral Infarction
- VernacularTitle:线粒体解耦联蛋白与脑梗死
- Author:
Rensi XU
;
Yuhui TAO
;
Yuchen WU
- Publication Type:Journal Article
- Keywords:
uncoupling protein;
cerebral infarction;
gene
- From:
International Journal of Cerebrovascular Diseases
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Uncoupling protein, a protein that participates in proton transport in the inner mitochondrial membrane, has some physiologic functions such as regulating thermogenesis, maintaining body temperature, regulating energy balance and adenosine triphosphate production, controlling reactive oxygen species production, and restraining apoptosis. It takes part in the pathophysiological processes in a number of diseases. The article reviews the uncoupling protein gene, distribution and regulation, the roles in peripheral tissues and central nervous system, and its possible relationship with cerebral infarction.
