Nerve Growth Factor and Neuroplasticity
- VernacularTitle:神经生长因子与神经可塑性
- Author:
Binru LI
;
Guinan BI
- Publication Type:Journal Article
- Keywords:
nerve growth factor;
neuroplasicity;
cerebrovascular disease
- From:
International Journal of Cerebrovascular Diseases
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Nerve growth factor may play its particular role in promoting the development of neuroplasticity after central nervous system and peripheral nerve injury. Its possible mechanisms are associated with regulation of TrkA receptor, activation of L-type calcium channel, promoting the release of acetylcholine, regulation of long-term potentiation and long-term depression. The study of the mechanisms of nerve growth factors for promoting neuroplasicity may provide novel therapeutic approaches for the treatment and rehabilitation of stroke, Alzheimer's disease, and peripheral nerve injury, and it may facilitate the development of the therapeutic drugs.
