STUDY ON THE ANTIOXIDANT ACTIVITY OF SWEET POTATO ANTHOCYANIN AND ITS INHIBITING EFFECT ON GROWTH OF CANCER S_(180)
- VernacularTitle:甘薯花青苷色素的抗氧化活性及抑肿瘤作用研究
- Author:
Guanlin WANG
;
Jing YUE
;
Dongxia SU
;
Hongjun FANG
- Publication Type:Journal Article
- Keywords:
sweet potato;
pigment;
antioxidant;
inhibiting cancer
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the antixiodant activity of sweet-potato anthocyanin (SPAC) and its inhibiting effect on growth of cancer S180. Method: The scavenging capacity of ??O2 and?OH and the inhibitory effect of MDA were determined in vitro.The SOD activity of serum and skin, the effect on S180 growth, serum GSH-Px activity and MDA were tested in mice. Results: SPAC had antioxidant activity in vitro, with elimination rate of O2?? and?OH 30.63% and 20.57% higher than the same concerntration of VC respectively. Activity of SOD in the serum and skin of mice were raised 27.30% and 13.50% respectively after giving SPAC. The growth rate of cancer S180 in the mice was inhibited, and the highest inhibitory rate was 43.12%. The activity of serum GSH-Px, SOD of the mice was raised as compared to control, but MDA declined . Conclusion: SPAC is a perfect natural pigment with inhibitory effect on growth of cancer S180 probably through its antioxidant activity.
