THE ATTENUATING EFFECT OF SOY ISOFLAVONES EXTRACT ON BONE LOSS IN POSTMENOPAUSAL WOMEN
- VernacularTitle:大豆异黄酮减缓绝经后妇女骨丢失的临床效应
- Author:
Yanbin YE
;
Yixiang SU
- Publication Type:Journal Article
- Keywords:
soybean isoflavones;
postmenopausal women;
bone loss;
bone mineral density
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of soy isoflavones extract on bone loss induced by estrogen deficiency. Methods: 87 postmenopausal women were randomly assigned in single blind manner, to three treatment groups with daily intake of placebo, 84 mg and 126 mg soy isoflavones respectively. Additionally a positive control group was 10 women was given daily 2.5 mg estrogen. Bone mineral density (BMD) of the lumbar spine, neck of femur and Ward`s triangle were measured at baseline and post treatment after 24 wk . Results: BMD in all sites in both isoflavones treated and estrogen treated groups did not change significantly. However, the BMD of the lumbar spine decreased in the placebo group (P
