Effects of total flavones metasequosia on ischemia reperfusion injury in guinea pig working heart
- VernacularTitle:水杉总黄酮对豚鼠工作心脏缺血再灌注损伤的影响
- Author:
Fang WANG
;
Enxin YU
;
Weiwan LIU
;
Zhiben TU
- Publication Type:Journal Article
- Keywords:
total flavones meatsequosia;
working heart;
reperfusion injury;
lipid peroxidation
- From:
Chinese Pharmacological Bulletin
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the effects of t ot al flavones metasequosia (TFM) on ischemia reperfusion injury in guinea pig work ing heart. METHODS Ischemia reperfusion injury model was used to evaluate the effects of TFM. Myocardial func tion, the content of CK、LDH and the activity of MDA were measured. RESU LT TFM improved the cardiac function, decreased the release of LDH and CK and inhibited the increase of MDA content. CONCLUSION TFM had a protective effect on ischemia reperfusion injury of myocardium which could be re lated to its inhibitory effect on lipid peroxidation.
