Studies on the mechanisms of TGF-?_1、TGF-?_1RⅡ and NF-?B on the angiogenesis In patients with hepatocellular carcinoma
- VernacularTitle:TGF-?_1、TGF-?_1RⅡ、NF-?B在肝细胞癌血管形成中的作用及机制探讨
- Author:
Guozhong JI
;
Zhiquan ZHAO
;
Lin MIAO
- Publication Type:Journal Article
- Keywords:
HCC\ TGF-? 1\ TGF-? 1RⅡ\ NF-?B\ Immunohistochemistry
- From:
Chinese Journal of Practical Internal Medicine
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanisms of TGF-? 1?TGF-? 1RⅡ and NF-?B on the angiogenesis in patients with hepatocellular carcinoma.Methods The expression of TGF-? 1 ?TGF-? RⅡ and NF-?B protein in 36 cases of HCC and surrounding HCC tissue was separately detected using immunohistochemistry technique.To observe the relationship of TGF-? 1 protein and MVD, TGF-? 1RⅡ protein and MVD, NF-?B and TGF-? 1 protein, using CD34 labelling vessel endothelial cell. Results The expression of TGF-? 1 and MVD in HCC tissue was higher than that in surrounding HCC tissue (P
