EFFECT OF HYPERBARIC OXYGEN ON ACTIVITY OF SUPEROXYGEN DISMUTASE AND CATALASE IN SPINAL CORD TISSUES AFTER SPINAL CORD INJURY
- VernacularTitle:高压氧对脊髓损伤大鼠脊髓组织中超氧化物歧化酶和过氧化氢酶活性的影响
- Author:
Jian FANG
;
Tiesheng HOU
;
Yiqu FANG
- Publication Type:Journal Article
- Keywords:
spinal cord injury;
hyperbaric oxygenation;
superoxide dismutase;
catalase
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the effect of hyperbaric oxygen (HBO) on the activity of superoxygen dismutase (SOD) and catalase (CAT) in spinal cord tissue, a rat spinal cord injury (SCI) model was established. The results showed that the activity of SOD and CAT in the spinal cord decreased significantly after injury, bat recovered after the treatment with 0 25MPa HBO and 0 25MPa HBO+hormone. These results suggest that HBO can increase the activity of anti oxidase in spinal cord,and prevent or relieve the injury by free radicals. Thus it can recover the function of spinal cord.
