EFFECTS OF FLAVONES OF CHOEROSPONDIAS AXILLARIS FRUCTUS ON IMMUNOLOGICAL FUNCTION IN MICE
- VernacularTitle:广枣总黄酮对小鼠免疫功能的影响
- Author:
Yuzhen WANG
;
Jianmei REN
;
Ruoyu WANG
- Publication Type:Journal Article
- Keywords:
Total flavones of Choerospondias axillaris;
Cyclophos-phamide;
cellular immunity;
humoral immunity;
Hemolysin;
Phagocytic activity of macrophage
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Total flavones were isolated from the fructus of choerospon-dias axillaris(Roxb. )Burrt et Hill ( TFC ) . TFC (40.32 and 20.16 nig/kg?d-1 , ip~5d) strengthened markedly functions of cellulae immunity and humoral immunity in normal mice as well as in immunodepressed mice induced by cyclophsphamide ( 25mg/kg?d-l, ih~2d). TFC caused a significant increase of the weights of spleen and thy-mus, and the production of serum hymolysin in normal and immunodepressed mice.TFC elevated normal titer of antibody induced by secondary antigen stimulation, and increased ANAE ( + ) cell percentage of lymphocyte and phagocytic activity of macrophages of abdominal cavity in normal and immunodepressed mice. TFC increaced the production of serum lysozyme in normal mice.
