TRANSPORT OF GOSSYPOL BY RAT EPIDIDYMIS
- VernacularTitle:棉酚在大鼠附睾中的转运
- Author:
Jianping CHOU
;
Juming WANG
;
Zhaorong ZHANG
- Publication Type:Journal Article
- Keywords:
Gossypold;
Epididymis;
Blood-epididymal barrier;
Transfer
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Transport of gossypol by rat cauda epidldymis has been studied using microperfusion technique. It was found that gossypol entered ep-ididymal duct at very much limited rate in spite of its high plasma level. There was no difference between the aqueous & liposome formulations of gossypol to get into the epididymal duct from the blood. Since it was indicated in a previous paper that the transport rates of the 2 gossypol formulations via the blood-testis barrier were quite different. It is suggested that the transfer mechanism in test-is & epididymis may be different.
