Relationship of hyperglycemia with intracranial pressure and neurological outcome after severe brain injury
- VernacularTitle:重型颅脑损伤后高血糖与颅内压及预后的关系
- Author:
Kaijie WANG
;
Aiguo CHENG
- Publication Type:Journal Article
- Keywords:
Brain injuries;
Glycemia;
Intracranial pressure;
Prognosis
- From:
Chinese Journal of Trauma
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of hyperglycemia on intracranial pressure (ICP) and neurological outcome following severe brain injury. Methods A retrospective review was done on 79 cases with severe traumatic brain injury (with no history of diabetes or important extracranial complications) who underwent craniotomy for evacuation of intracranial hematoma and were divided into two groups based on Glasgow outcome scales (GOS) score, ie, favorable group with GOS of 5 or 4 and unfavorable group with GOS less than 3. Statistical analysis of data was accomplished by using SPSS 11.5 software. The outcome was assessed at the 6th month after injury. Results A significant correlation was found between ICP levels and admission or postoperative glucose values. The unfavorable group had significantly higher glucose levels both on admission and after operation compared with the favorable group, with statistical difference (P
