A preliminary study on intravesical capsaicin for the treatment of obstinate urethral syndrome
- VernacularTitle:辣椒辣素治疗顽固性女性尿道综合征初探
- Author:
Zhichen GUAN
;
Daoheng ZHANG
;
Tong CHEN
- Publication Type:Journal Article
- Keywords:
Urethral disease;
Capsaicin;
Urodynamics;
Therapeutics
- From:
Chinese Journal of Urology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate intravesical capsaicin for the treatment of obstinate urethral syndrome in female. Methods Thirty two female patients suffering from urethral syndrome not relieved on various therapeutic methods for a long time were treated by bladder instillation of 100 ml of 100 ?mol/L capsaicin. Results 15 cases were followed up for more than 12 months with improvement in 94%.The symptoms were totally disappeared in 33% of the patients.The syndrome recurred in 53% between 3~6 months. 1 case did no response to the treatment. Bladder instillation of capsaicin induced an increase of the bladder volume.Some burning sensation was the only side effect. Conclusions Intravesical capsaicin could be a long lasting effective therapeutic method for patients with obstinate urethral syndrome.