The protective effect of nifedipine for acute renal function impairment caused by ESWL
- VernacularTitle:硝苯地平对ESWL致急性肾脏损伤的保护作用
- Author:
Yingmin XU
;
Weizhong GAO
;
Chunxiao XU
- Publication Type:Journal Article
- Keywords:
Urinary calculi;
Extracorporeal shock wave lithotripsy;
Kidney failure,acute
- From:Chinese Journal of Urology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of nifedipi ne ,an endothelin antagonist,in acute renal function impairment caused by ESWL. Methods 60 cases of renal stone underwent anaesthesia-free ESWL were radomely assigned into 2 groups,the nifedipine group and the control (n=30 each).In the former group,nifedipine was given 3 days before ESWL.Plas ma endothelin,urinary ? 2-microglobulin,and urinary Tamm-Horsfall protein we re assessed to evaluate the renal function. Results In t he controls,it was a significant increase of plasma endothelin and urinary ? 2-MG(P
