Relationship between Serum Leptin Level and RAAS,Insulin Sensitivity in Patients with Obesity-related Hypertension
- VernacularTitle:肥胖高血压患者血清瘦素与肾素-血管紧张素-醛固酮系统及胰岛素相关性分析
- Author:
Ying HAO
;
Bin ZANG
- Publication Type:Journal Article
- Keywords:
Hypertension;
Obesity;
Leptin;
Insulin;
Renin-angiontensin system;
Aldosterone
- From:
Chinese Journal of Prevention and Control of Chronic Diseases
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the relationship between serum leptin level and RAAS,insulin sensitivity.Methods We collected 38 patients with obesity-related hypertension,32 patients with hypertension,33 patients with obesity and 33 normal controls.Their serum levels of Leptin,FINS,PRA,AngⅡ,ALD and FPG were measured,and then the insulin sensitivity index(ISI) was calculated.Their body height and weight were measured,and body mass index(BMI) was calculated.Results ISI levels in patients with obesity-related hypertension,with hypertension or with obesity were significantly lower than that in the control(P
