Study on the Protective Effect of Traditional Chinese Medicine that Invigorating Vital Energy and Pro-moting Blood Flow on Model of Renal Ischemical Reperfusion Injury of Rats
- VernacularTitle:补气活血中药对肾缺血再灌注损伤模型大鼠的保护作用研究
- Author:
Bin YAN
;
Jianhua WANG
;
Xudong WANG
;
Xinli CAO
;
Zhengu LAI
;
Xingmei HE
;
Jian ZHANG
- Publication Type:Journal Article
- Keywords:
Traditional Chinese medicine that invigorating vital energy and promoting blood flow;
Rats;
Renal ischemical reperfusion injury;
Protective effect
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:Approach to the protective effect of traditional Chinese medicine that invigorating vital energy and promoting blood flow on model of renal ischemical reperfusion injury of rats.METHODS:The rats were divided into control group,model group and medication group(traditional Chinese medicine that invigorating vital energy and promoting blood flow),the medication group were given prevention administration for7days;model of renal ischemical reperfusion injury of rats were established.The contents of complement C3and nitric oxide(NO)in serum and renal tissue and the pathological changes of renal tissues in each group were compared.RESULTS:Levels of complement C3and NO in serum and renal tissue were increased in the model group and there were obvious pathological changes in renal tissues;compared with the model group,there was a decrease in the contents of complement C3and NO in serum and renal tissues and there was an obvious improvement in the renal tissues in the medication group.CONCLUSION:The traditional Chinese medicine that invigorating vital energy and promoting blood flow has a protective effect on the model rats with renal ischemical reperfusion injury.
