Clinical Observation on Compound Glycyrrhizin Combined with Interferon?-2b in the Treatment of Chronic Hepatitis B
- VernacularTitle:复方甘草酸苷联合干扰素?-2b治疗慢性乙型肝炎疗效观察
- Author:
Chengji LU
- Publication Type:Journal Article
- Keywords:
chronic hepatitis B;
compound glycyrrhizin;
IFN?-2b
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the clinical effect of compound glycyrrhizin combined with interferon?-2b for treating chronic hepatitis B(CHB).METHODS:A total of74CHB patients were randomized into group A and group B,which were given large-dose of compound glycyrrhizin combined with interferon?-2b,and the same dose of interferon?-2b alone for24weeks respectively,and followed up for6months.RESULTS:By the end of therapeutic course,the ALT recovery rates of both groups were high,however,the rates of negative conversion of HBeAg and HBV-DNA,and the ALT recovery rate in follow-up period were more satisfactory in group A than those in group B.CONCLUSION:Compound glycyrrhizin combined with IFN?-2b has better anti-HBV effect.
