Renal Protective Effect of Perindopril in Diabetic Rats
- VernacularTitle:培哚普利对糖尿病大鼠肾脏的保护作用
- Author:
Huiju ZHONG
;
Dongmei ZHANG
;
Min ZHOU
- Publication Type:Journal Article
- Keywords:
Perindopril;
Diabetes mellitus;
Urinary albumin excretion;
Renal ultrastructure
- From:
Journal of Chinese Physician
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the renal protective effect of perindopril in diabetic rats. Methods The following groups of rats were studied: normal control rats ,diabetic control rats and diabetic rats treated with perindopril (2mg?kg -1 ?d -1 ) . After 4 weeks or 12 weeks treatment , alterations of renal ultrastructure were observed in each group, Urinary albumin excretion was observed every 4 weeks.Results Urinary albumin excretion of diabetic rats treated with perindopril were significantly lower than that of diabetic untreated group(P
