The effect of injection repeatedly of monosodium glutamate on the body temperature in rabbits
- VernacularTitle:谷氨酸钠反复注射对家兔体温的影响
- Author:
Hong LI
;
Daxiang LU
- Publication Type:Journal Article
- Keywords:
Body temperature;
Sodium glutamate;
Rabbit
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Further study of the effect of monosodium glutamate on body temperature using rabbits as experimental model by repeatedly intravenous injection of MSG. The experimental results showed that the body temperature of rabbits were decreased significantly at a time of each day consecutively for three days with medium dose MSG(0.5g/kg/day) However, this effect was disappeared following the fourth administration of MSG a week later, and so did the fifth administration of MSG two weeks later. Those results suggested that the disappearance of decreased body temperature by MSG may be due to tolerance development after MSG was administrated repeatedly. The authors proposed two hypotheses of mechanisms for the development of MSG"tolerance". which would be investigated further.
