Effect of different gosages of oxytocin on infantile pathological jaundice
10.3969/j.issn.1005-1678.2017.02.048
- VernacularTitle:产程中静滴不同剂量缩宫素对新生儿发生病理性黄疸的影响
- Author:
Xiaoyan YAO
;
Shengqun XIANG
;
Can JIN
;
Lingxian ZHU
- Keywords:
labor;
oxytocin;
pathologic jaundice;
neonatal
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(2):159-161
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of different oxytocin doses on neonatal pathologic jaundice.Methods A total of 386 newborn infants with normal term of labor were selected from the full-term pregnant women who were admitted to Jiaxing Maternal and Child Health Care Hospital from August 2014 to September 2015 were divided into low dose group (2.5 ~5.0U,n=96), middle dose group (5.0 ~7.5U,n=96), high dose group (7.5~10.0U,n=96) and control group (n=98) according to the different dosage of oxytocin.Total labor time, neonatal gender, neonatal weight and maternal age, as well as the day of birth within seven days of skin side of the bile values were recorded.The probability of each group of neonatal patients with pathological jaundice and the relationship with oxytocin doses were studied.Results The incidence of neonatal pathologic jaundice was 3.23%in the low dose group, 6.67%in the middle dose group, 29.73%in the high dose group and 3.16%in the control group.The differences among low dose group, middle dose group and control group were not significan.Compared with high dose group, the incidence of neonatal pathologic jaundice in low dose group, middle dose group, and the control group were all lower(P<0.05).Conclusion Oxytocin less than 7.5U in labor has no significant effect on neonatal pathologic jaundice, >7.5U can promote pathologic jaundice.
