Analysis of One Case of Senior Patient with Deep Vein Thrombosis Occurred Retroperitoneal Bleeding during Anticoagulant Therapy
- VernacularTitle:1例深静脉血栓老年患者抗凝治疗致腹膜后出血的病例分析
- Author:
Sha MA
;
Shun ZOU
;
Jinhua ZHANG
- Keywords:
Deep vein thrombosis;
Anticoagulation;
Bleeding;
Elderly
- From:
China Pharmacist
2017;20(4):680-683
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To improve the recognition of bleeding risk in the anticoagulant process by analyzing one case of senior patient with deep vein thrombosis occurred severe bleeding during the anticoagulant therapy.Methods:The possible causes of hemorrhage were analyzed after the brief introduction of medical history,lab test report and treatment process of the patient.Results:The reasons of hemorrhage might be as follows:① the combination of warfarin and dalteparin induced the adverse drug reaction;② albumin decreased during the treatment process resulting in the effect enhancement of warfarin;③ the clearance of warfarin decreased resulting from the low creatinine clearance of the elderly patient.Conclusion:Clinical anticoagulant practice should be more careful in senior patients.The frequency of related laboratory tests should be increased in order to find potential risks timely.