Clinical Observation of Compound Huanglian Jiangtang Powder for Patients with Impaired Fasting Blood Glucose
10.6039/j.issn.1001-0408.2016.17.18
- VernacularTitle:复方黄连降糖散治疗空腹血糖受损患者的临床观察Δ
- Author:
Guochao CHEN
;
Xiaoli LI
;
Liping LI
- Publication Type:Journal Article
- Keywords:
Compound huanglian jiangtang powder;
Impaired fasting blood glucose;
Therapeutic efficacy;
Safety
- From:
China Pharmacy
2016;27(17):2358-2360
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe clinical efficacy and safety of Compound huanglian jiangtang powder for patients with im-paired fasting blood glucose(FBG). METHODS:122 patients with impaired FBG were selected and randomly divided into control group and trial group with 61 cases in each group. Two groups was given healthy education and diet guidance;trial group was giv-en Compound huanglian jiangtang powder 2.5 g orally,qd. Both groups were treated for 4 months. Clinical efficacy of 2 groups was observed and FBG,TC,TG,LDL-C,HbA1c,SOD,MDA and GSH-PX levels and BMI were observed before and after treat-ment. The occurrence of ADR was recorded. RESULTS:Total effective rate of trial group was 77.0%,which was significantly higher than that of control group(24.6%),with statistical significance(P<0.05). Before treatment,there was no statistical signifi-cance in FBG,TC,TG,LDL-C,HbA1c,SOD,MDA and GSH-PX levels and BMI between 2 groups (P>0.05);after treat-ment,above indexes of 2 groups were improved significantly,the trial group was significantly better than the control group,with statistical significance(P<0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Compound huanglian jiangtang pow-der is effective improvement of laboratory indexes and safe for impaired FBG.
