Role of oncogene and tumor suppressor gene in tumor metabolic reprogramming
10.3969/j.issn.1005-1678.2016.09.001
- VernacularTitle:肿瘤代谢重编程中的癌基因与抑癌基因
- Author:
Xinyuan XU
;
Lan SHEN
;
Libo YAO
- Publication Type:Journal Article
- Keywords:
tumor;
metabolic reprogramming;
oncogene;
tumor suppressor gene
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(9):1-5
- CountryChina
- Language:Chinese
-
Abstract:
With the understanding of tumor metabolism, the process and mechanism of tumor metabolic reprogramming gradually attracted much attention in recent years.Oncogenes and tumor suppressor genes are constantly changing the pathway and flux of tumor metabolism in tumorigenesis to meet the needs of tumor growth and proliferation.The role of c-MYC, TP53, HIF-1αas well as the related signal pathways in tumor metabolic reprogramming would be discussed.
