Efficacy and Safety of Compound Yimucao Oral Liquid Combined with Oxytocin in the Prevention of Post-partum Hemorrhage and Promotion of Uterine Involution for Puerpera of Vaginal Delivery
10.6039/j.issn.1001-0408.2015.33.07
- VernacularTitle:复方益母草口服液联合缩宫素预防阴道分娩产妇产后出血及促进子宫复旧的效果与安全性
- Author:
Wei ZHANG
;
Guohui DU
;
Dongmei CAO
;
Wei XIE
;
Kun QIAN
;
Guilan YU
;
Haiying JIANG
- Publication Type:Journal Article
- Keywords:
Compound yimucao oral liquid;
Oxytocin;
Vaginal delivery;
Postpartum hemorrhage;
Uterine involution;
Effica-cy;
Safety
- From:
China Pharmacy
2015;26(33):4629-4631
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efficacy and safety of Compound yimucao oral liquid combined with oxytocin in the prevention of postpartum hemorrhage and promotion of uterine involution for puerpera of vaginal delivery. METHODS:240 preg-nants with natural childbirth of vaginal delivery were randomly divided into control group and observation group. Control group was injected oxytocin 20 U in buttock after delivery. Observation group was additionally treated with Compound yimucao oral liquid 20 ml,tid for consecutive 2 weeks. Postpartum vaginal bleeding,uterine involution and incidence of adverse reactions in 2 groups were observed. RESULTS:Compared with control group,postpartum hemorrhage volume after delivery 2-24 h,incidence of post-partum hemorrhage,uterus size,uterine hemorrhage and lochia duration in postpartum 42 d in observation group were significantly better than control group,the differences were statistically significant(P<0.05);there were no significant differences in the hemor-rhage postpartum volume after delivery 1 h and 1-2 h and fundal height in postpartum 42 d in 2 groups(P>0.05). There were no fever,rash,nausea and other obvious adverse reactions in 2 groups. CONCLUSIONS:Compound yimucao oral liquid combined with oxytocin can obviously decrease the postpartum bleeding and promote uterine involution,with good safety.
