Recent advances in neuroprotective effect of histone deacetylase inhibitors
10.3969/j.issn.1005-1678.2016.06.61
- VernacularTitle:组蛋白去乙酰化酶抑制剂的神经保护作用研究进展
- Author:
Xianlei YAN
;
Heqing HUANG
- Publication Type:Journal Article
- Keywords:
histone deacetylase inhibitors;
nervous injuries;
neuroprotective
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(6):200-203
- CountryChina
- Language:Chinese
-
Abstract:
Objective Central nervous system trauma, ischemia, hemorrhagic stroke were all experienced the same pathological damage, in related animal experiments,histone deacetylase inhibitors have a wide range of neuroprotective effect, it is expected to become a new class of potential therapeutic agents.However,the specific mechanism is not clear.In this paper, the research progress of neuroprotective effect of histone deacetylase inhibitors is reviewed,in order to improve recognition of histone deacetylase inhibitors and provide foundation for futher study.
