Advance in Studies on Anti-inflammatory Mechanism of Flavonoids
- VernacularTitle:黄酮类化合物抗炎作用机制研究进展
- Author:
Bo YANG
;
Yin YING
;
Lingli CHEN
;
Chengle LI
- Publication Type:Journal Article
- Keywords:
Flavonoids;
Anti-inflammation;
Mechanism
- From:
China Pharmacist
2016;19(7):1369-1373
- CountryChina
- Language:Chinese
-
Abstract:
Flavonoids are the secondary metabolites of plants , which are found in many plants .Flavonoids have extensive phar-macological actions , such as anti-inflammation, anti-tumor, anti-bacteria and anti-virus, scavenging free radicals , osteoporosis preven-tion and cardiovascular protection .Based on the analysis of relative literatures published at home and abroad in recent years , the mech-anisms of anti-inflammatory effects of flavonoids were reviewed , including arachidonic acid metabolism pathway , cytokine and its recep-tor, cell second messenger, active oxygen, nitrogen monoxide, platelet activating factor and its receptor , nuclear factor, intercellular adhesion molecule and so on .The review aimed to provide theoretical basis for the further development and research .